14. Digital ischemia and interstitial lung disease in antisynthetase syndrome with PL-12 antibody
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چکیده
منابع مشابه
Tacrolimus for antisynthetase syndrome with interstitial lung disease?
The methodology used in the two devices is different but this is unlikely to explain the differences reported in this study. Indeed, no difference was detected when samples of known NO concentrations ranging 5–100 ppb and ambient air were analysed with both devices (p50.18 by paired t-test). Therefore, differences in expiratory manoeuvres were considered. A micro-spirometer connected to the NIO...
متن کاملInterstitial lung disease in antisynthetase syndrome without clinical myositis.
To cite: Sundaragiri PR, Vallabhajosyula S, Kanaan JP. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2014204296 DESCRIPTION Antisynthetase syndrome (ASS) is a lesser recognised idiopathic inflammatory myopathy with nearly 89% showing interstitial lung disease (ILD). However, in a small subpopulation without evidence of myositis, the diagnosis may be critically d...
متن کاملDevelopment of myasthenia gravis 8 years after interstitial lung disease associated with antisynthetase (anti‐EJ antibody) syndrome
Patients with antisynthetase-positive interstitial lung disease (ILD) alone sometimes develop myositis during follow-up, but myasthenia gravis (MG) overlapping on antisynthetase syndrome is unusual. A 56-year-old woman with ILD and anti-EJ antibody treated for 8 years developed MG. Physicians should consider myositis and MG when patients develop muscle symptoms during follow-up.
متن کاملSyndrome in question: antisynthetase syndrome (anti-PL-7)*
Antisynthetase syndrome is a rare autoimmune disease characterized by interstitial lung disease and/or inflammatory myositis, with positive antisynthetase antibodies (anti-Jo-1, anti-PL-7, anti-PL-12, ZO, OJ, anti-KE or KS). Other symptoms described include: non-erosive arthritis, fever, Raynaud's phenomenon, and "mechanic's hands." The first therapeutic option is corticotherapy, followed by ot...
متن کاملAcute digital ischemia: A rare presentation of antisynthetase syndrome.
Antisynthetase syndrome (ASS) is recognized as a subgroup of idiopathic inflammatory myopathies (IIMs). It is associated with autoantibodies directed against aminoacyl-transfer ribonucleic acid (tRNA) synthetase enzymes. We report the first case of anti-PL-7/anti-SSA 52kD ASS presenting as acute digital ischemia, an association not described previously. Occlusive vasculopathy is a rare but seri...
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ژورنال
عنوان ژورنال: Rheumatology Advances in Practice
سال: 2019
ISSN: 2514-1775
DOI: 10.1093/rap/rkz030.013